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WHAT LDD™ IS AND WHAT IT IS USED FOR
LDD™ (low dose dipyridamole) is a proprietary low dose formulation of the medicine dipyridamole. Dipyridamole has been used since the 1960’s for treating hypercoagulation disorders and reducing the risk of heart attacks and stroke. The traditional dose of dipyridamole varies from 200 – 225 mg daily in most countries, and 400 mg daily as approved by the US Food and Drug Administration.
The low dose of dipyridamole (2 mg) used in LDD™ capsules is being studied for a number of medical conditions. These include the treatment or prevention of viral disorders, treatment or prevention of insomnia, treatment of dry eye disease, and pain-reducing effects.
Dipyridamole has well-established properties that include multiple anti-inflammatory and anti-viral effects. The novel mechanisms of action of dipyridamole when used in low doses, are the subject of ongoing scientific study.
LDD™ is available in 2 mg capsules.
BEFORE YOU USE LDD™
Ensure that the package of LDD™ is in date, and that individual capsules are properly sealed. If you are are due to undergo any surgical procedure, discuss your LDD™ use first with your physician or pharmacist.
Using other medicines The low dose of dipyridamole used in LDD™ is not known to interact with other medicines. However, please inform your doctor or pharmacist of any changes or additions to the medications you are using. If you are using anti-ulcer drugs (such as antacids or proton-pump inhibitors), you may need to double the dose of LDD™ to achieve efficacy.
Taking LDD™ with food and drink LDD™ is best absorbed when taken on an empty stomach at least 30 minutes before food or 2 hours after food. If taken with food, double the dose may be needed.
Pregnancy and breast feeding Studies have shown positive effects on reversing fetal growth retardation in women taking high dose dipyridamole during pregnancy. Animal studies have not shown any risks when used during pregnancy. Dipyridamole is classified as Category B by the US FDA for use in pregnancy. Category B means that animal studies have not shown a risk to the fetus yet there are no adequate and well-controlled studies in pregnant women.
Dipyridamole is excreted into human milk in small amounts. There are no reports of adverse events in infants secondary to breast feeding during dipyridamole administration.
If you are pregnant or plan becoming pregnant, or breast feeding, discuss this with your health care professional before starting to use LDD™.
HOW TO USE LDD™
LDD™ can be taken once or more daily. When used for treating insomnia or sleep disorders, LDD™ should be taken in the evening or before sleep. As absorption of the dipyridamole in LDD™ varies between individuals, the dose may be increased if needed until a therapeutic benefit is observed. However, LDD™’s unique benefits typically do not occur at doses that exceed 10 – 20 mg daily.
LDD™ should be swallowed with the aid of water or another liquid.
POSSIBLE SIDE EFFECTS
Like all medicines, LDD™ can cause side effects, although not everybody gets them. If you notice any prolonged side effects that do not resolve quickly, or any exacerbation in your symptoms, please tell your doctor or pharmacist.
It is not unusual for LDD™ to cause vivid dreams or improved dream recall. If you find these disturbing, you can try to avoid taking LDD™ at night.
HOW TO STORE LDD™
Keep out of the reach and sight of children.
Store at room temperature, away from any sources of direct light, heat, or moisture.
Do not use LDD™ after the expiry date stated on the package The expiry date refers to the last day of the month and year stated on the package.
What LDD™ contains - The active substance is dipyridamole 2 mg. - The only other ingredient is pure dextrose monohydrate used to allow immediate release of the naltrexone. No other fillers or binders are used. - Capsule shell is made from gelatin, and is certified Kosher.