Cepharan™ is our exclusive brand of cepharanthine. Cepharanthine is approved in Japan for treating alopecia areata, and as an adjunct to radiation therapy to prevent anemia and thrombocytopenia. It is also used to treat various cancers, autoimmune diseases, and allergy conditions. In 2015 it was discovered that cepharanthine can also treat male pattern baldness or androgenic alopecia.

Cepharan™ contains cepharanthine, a pure natural extract of the Stephania cepharantha Hayata plant. Cepharan™10 is used in the treatment of cancer and autoimmune disorders, where total doses of 30 - 60 mg (3 - 6 capsules of 10 mg each) daily are given. Cepharan™2 is used for the treatment of different types of hair loss such as alopecia areata and androgenetic (androgenic) alopecia also known as male pattern baldness.

Did you know?

Cepharan™ contains the plant extract cepharanthine derived from the Stephania cepharantha Hayata plant. This rare species of Stephania is native to the Kotosho Island, southeast of Taiwan. It is a member of the Menispermaceae family, and now grows in the mountain regions of southwest China and Taiwan. Cepharanthine is extracted from the roots of the plant.

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What is Cepharan™ (Cepharanthine) Used For?

Cepharan™2 is used to treat hair loss, such as alopecia areata, and androgenic (androgenetic) alopecia also known as male pattern baldness. Cepharan™10 is used to treat different types of cancer including hematologic malignancies, as an adjunct to chemotherapy and radiation, helping to preserve healthy hemoglobin and platelet counts. It is also used to treat a wide range of autoimmune diseases and allergy conditions. Successful clinical studies have been published about the use of cepharanthine for treating Sjögren’s Syndrome, idiopathic thrombocytopenic purpura (ITP), nodular muscular sarcoidosis, radiation induced leukopenia, metastatic renal cell carcinoma, prostate cancer, multiple myeloma, and more.

To learn about cepharanthine, the disorders and diseases it works for, and the latest studies, visit cepharanthine.org

Cepharan™ Questions & Answers

  1. What is Cepharan™?

    Cepharan™ contains cepharanthine, a natural alkaloid extracted from the plant Stephania cepharantha Hayata. It is approved as a medicine in Japan, where it is used to treat a wide variety of acute and chronic diseases, acting through multiple biochemical and pharmacological mechanisms.

  2. Which medical conditions can benefit, or be treated with Cepharan™?

    Cepharan™ has successfully been used to treat a diverse range of medical conditions, including leukopenia caused during radiation therapy, idiopathic thrombocytopenic purpura (a low platelet count without obvious cause), alopecia areata, alopecia pityrodes, venomous snake bites, and aspects of cancer management.

  3. How does Cepharan™ work?

    The cepharanthine contained in Cepharan™ has been shown to have multiple biochemical effects. Some of these include:
    ● Membrane-stabilizing effect
    ● Inhibition of platelet aggregation
    ● Inhibition of plasma membrane lipid peroxidation
    ● Antitumor activity
    ● Inhibition of histamine release
    ● Immunomodulatory effects
    ● Anti-inflammatory effects
    ● Apoptosis-inducing effects
    ● Anti-allergic effects
    ● Free-radical scavenging effects
    ● Multi-drug resistance-reversing effects
    ● Anti-HIV effects
    ● Chemotherapy-potentiating effects
    ● Anti-malaria effects

  4. How quickly does Cepharan™ work?

    Effect varies by disease being treated. However, it typically takes just a few weeks to start experiencing the beneficial effects of Cepharan™.

  5. Which dose do I need?

    For the treatment of hair loss (alopecia), the usual dosage for an average adult is a total of is 2 mg per day, sometimes going up to 6 mg daily if needed. For treating cancer, or autoimmune diseases, daily doses range from 30 to 60mg. As an adjunct to radiotherapy, to help prevent leucopenia or other blood count disturbances, a dose of 10 mg daily may suffice.

  6. When should Cepharan™ be taken?

    The total daily dosage can be taken at once or divided across two or three doses, to be taken orally after meals.

  7. Which medications must be avoided when using Cepharan™?

    There are no known medications which need to be avoided when using Cepharan™.

  8. What are the side effects of Cepharan™?

    Cepharanthine has an enviable safety and tolerability profile. Over many years of usage in Japan, very minor side effects (such as gastrointestinal upset) have been reported in only one of every 140 users.

  9. Can I use Cepharan™ while pregnant?

    The use of any medicinal product during pregnancy should be discussed with your physician.

Cepharanthine Resources

Cepharanthine review article  in Pharmacological Reports

Cepharanthine 2019 review article  in Phytomedicine

Cepharanthine for COVID-19 review article  in Pharmacological Reports

Cepharanthine education site cepharanthine.org