From Chronic Pain to Blissful Relief with NaltrexLow™

We all experience pain sometimes. Although it can be unpleasant, pain exists for a purpose.

Pain is the way our body warns us of danger. An example of this is the pain we feel when we touch something very hot. A serious burn could result if pain wasn’t there to alert us to withdraw our hand. If it didn’t hurt to walk on a broken leg, we would continue to do so, which would prevent the leg from healing. Pain is a message from our minds that is trying to protect us from physical harm, and it's controlled by our brain’s assessment of our own safety needs.

Ordinary pain is the result of an injury or an illness and it disappears when one is healed. Chronic pain is different because it has no biological value and extends past its original causes. This means that the body continues to send pain signals to the brain for months or even years after one has healed. Some people even suffer from chronic pain that has no apparent initial trigger.

Presently, over 40 million adults in the US suffer from a chronic pain condition.

There are several definitions of what constitutes as chronic pain. While some doctors classify chronic pain as any pain that lasts longer than three to six months, others define it as “pain that extends beyond the expected period of healing”.

"People often didn't understand how difficult tiny tasks were...I couldn't sit without pain, so I stopped driving, working, and traveling.”

As a result of being unable to continue life as they did previously, people who suffer from chronic pain can also become irritable, anxious, and depressed.

"I became increasingly unwell from an emotional/psychological standpoint. I felt angry, bitter, hopeless, and powerless to change my circumstances."

When chronic pain is left untreated, it causes pathological changes to the central nervous system. These changes cause patients to become more sensitive to pain over time so that even the feelings of ordinary touch or light pressure can become painful.

While non-steroidal pain killers are frequently prescribed to treat chronic pain, they carry the risk of negative side effects such as gastrointestinal bleeding, kidney injury, and increased risk of stroke. Other common treatments are opioid medications, which are infamous for being highly addictive and may even become ineffective once the body gets accustomed to them.

“I was on those (opioid) medications for 12 years. A couple times the pain got so bad, I took more than my usual amount. But if you run out of your medication early and you need more (because you can’t do without it), you are looked at like a criminal... I wanted off those medications.”

These challenges have inspired doctors to seek an alternative and safer solution for pain management. Research has led to the recognition of the non-addictive low dose naltrexone (LDN) due to its novel ability to safely relieve pain and enhance quality of life.

In order to understand how LDN treats chronic pain, we must understand what causes chronic pain in the first place.

Many doctors postulate that a chronic pain disorder is auto-immune based and caused by over-active microglia. Microglia are cells that react whenever they sense an attack on the central nervous system. The microglia respond to the suspected attack by releasing inflammatory substances in the body in efforts to fight the attack and protect the body. The microglia are meant to return to their resting state when the attack is over. However, if the microglia are activated too often due to recurrent injuries, infections or other physical/emotional traumas- they may keep the brain in a constant state of inflammation which impairs brain function and causes chronic pain.

LDN may be one of the first medications able to treat chronic pain disorder by acting as a glial cell modulator. Evidence has shown that LDN suppresses the activation of microglia, thereby reducing brain inflammation and results in significant pain relief.

Another mechanism by which LDN provides pain relief is by fixing the body’s own production of pain-kiling endorphins. Endorphins are the “feel-good” hormones the body produced naturally. The word “endorphin” is a combination of “endo” - or self produced - “morphin” - the “feel good” drug. Clinical investigations have shown that chronic pain patients have abnormally low levels of natural endorphins. Low levels of endorphins are associated with physical pain and feelings of depression. Endorphins play an essential role in regulating the immune system and providing pain relief.

One feature of LDN is that it blocks the natural endorphin release system in the body for several hours. This block causes the brain to think it needs to increase endorphin production. When the block wears off, the body is flooded with all the beneficial endorphins it produced, which remain in the body providing relief for the rest of the day.

LDN has been shown to increase the endorphin levels in the body by 300%!

According to Dr. Andrew David Schiller, a pain specialist and graduate of Harvard Medical School:
“LDN works in a way that is unlike other drugs. With most drugs, the medication itself is meant to have some therapeutic or symptom blocking effect. LDN is the opposite. Your body’s response to LDN is what creates the therapeutic effect. This is part of why LDN often helps many people when conventional medicine fails.”

Patients have reported:
“LDN has drastically improved my life, reopening doors of hiking without pain, and playing the guitar after 7 years of not being able to play. I move much better and feel much better!”

“I've been thrilled to find that it has reduced my pain to the point where I no longer feel held back from doing anything I would have done before.”

“If you’ve tried everything else, give this a try. If you’re new to this journey, find a doctor that knows about LDN and give it a try. Be proactive about your care. If you don’t fight for your health no one else will. If you’re not being listened to–keep searching for a doctor who hears what you’re saying. I am grateful...specifically for LDN.”

We invite you to try achieving a new life without pain (or risky medications). NaltrexLow™ is our specialized brand of LDN, available only at, where we are committed to providing you with top quality medications and exceptional service. NaltrexLow™ is available now with a 100% satisfaction guarantee or your money back. We’re here to help you every step of the way, so please contact us with any questions you may have.